PDRN & Sponge Spicules: The Perfect Combination of Regeneration and Penetration
Dear Customers,
In modern skincare, the success of a formulation depends not only on the efficacy of an active ingredient, but also on its ability to reach the area where it can deliver its benefits.
Currently, PDRN (Polydeoxyribonucleotide) is one of the most exciting trends in skin repair, longevity, and well-aging. This active ingredient, well known from aesthetic medicine, has been valued for years for its regenerative properties and is typically injected directly into the skin.
However, this is precisely the challenge for cosmetic applications: due to its molecular size, PDRN has limited ability to penetrate the skin barrier. To fully leverage its potential, innovative technologies are needed to support active ingredient delivery.
This is where Sponge Spicules come into play. By activating the skin and creating temporary microchannels, they can help enhance the penetration of subsequently applied active ingredients.
As a result, the combination of PDRN and Sponge Spicules opens up new possibilities for utilizing innovative actives from aesthetic medicine in advanced cosmetic applications.
PDRN – DNA-Based Regeneration
PDRN (Polydeoxyribonucleotide) consists of short DNA fragments and originates from aesthetic medicine. Due to its regenerative potential, PDRN is increasingly becoming a key component of modern skin repair and longevity concepts.
For cosmetic applications, we offer two innovative polynucleotide solutions.
PDRN from Salmon (Sodium DNA)
Our Sodium DNA is derived from salmon DNA and is based on the type of raw material that has been used in professional aesthetic applications for many years.
Benefits
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Well known from professional polynucleotide treatments in aesthetic medicine |
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Supports the regeneration of stressed and challenged skin |
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Ideal for skin repair, post-treatment, and longevity concepts |
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DNA-based active ingredient for modern regenerative skincare concepts |
PDRN from Laminaria digitata
In addition to our classic Sodium DNA, we offer an innovative plant-based alternative derived from the brown algae Laminaria digitata.
Benefits
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Innovative plant-based polynucleotide source |
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Supports the regeneration of stressed and challenged skin |
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Ideal for skin repair, post-treatment, and longevity concepts |
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Plant-derived active ingredient for innovative formulations |
Sponge Spicules – Innovative Technology for Optimized Active Ingredient Delivery
Even the most effective active ingredients can only reach their full potential if they can overcome the skin barrier.
Our Sponge Spicules consist of natural microscopic needle-like structures derived from marine sponges. During application, they create temporary microchannels on the skin surface, helping to support the penetration of subsequently applied active ingredients.
This creates a particularly interesting concept when combined with PDRN: while the Sponge Spicules prepare the skin for enhanced active ingredient uptake, PDRN can effectively deliver its regenerative benefits. This opens up new opportunities to bring active ingredients from aesthetic medicine into modern cosmetic applications.
Why Are Our Sponge Spicules Not Vegan?
Our Sponge Spicules are derived from natural sponges and are therefore not vegan.
Many alternatives marketed as vegan are based on mineral microstructures, such as borosilicate or calcium aluminum borosilicate systems, designed to mimic the function of natural Sponge Spicules.
The Natural Origin of Our Sponge Spicules Offers Significant Advantages
99 % Purity
Through careful processing, our Sponge Spicules achieve a purity level of up to 99%.
High Proportion of Intact Spicules
A key quality factor is the high proportion of fully intact needle structures. This enables uniform and reproducible skin activation.
Natural Microstructure for Enhanced Active Delivery
The needle-like structures support the penetration of subsequently applied active ingredients and create optimal conditions for innovative skin repair and longevity concepts.
The Ideal Complement to PDRN
Together, Sponge Spicules and PDRN create new opportunities for modern cosmetic formulations focused on regeneration, skin repair, and longevity.
Spicura
Activate. Infuse. Shield.
With Spicura, we present an exemplary formulation concept that illustrates the synergistic combination of Sponge Spicules and PDRN, integrating activation, regeneration, and barrier protection into one holistic approach.
1. Spicura Activate
Activating Gel Mask with Sponge Spicules
In the first step, the skin is activated with Sponge Spicules and optimally prepared for the absorption of subsequent active ingredients.
Objective: Skin activation and support of active ingredient penetration.
Download the product description for Spicura Activate as a PDF here.
2. Spicura Infuse
Regenerating Serum with PDRN
Following the activation step, a serum containing PDRN is applied.
Objective: Support skin regeneration and promote a healthy, even, and revitalized complexion.
Download the product description for Spicura Infuse as a PDF here.
3. Spicura Shield
Barrier Cream for Protection and Maintenance of the Skin Barrier
The treatment concludes with a Barrier Cream containing selected active ingredients to support the skin barrier after treatment.
Objective: Maintain and strengthen the skin barrier, support skin soothing, and minimize redness and feelings of tightness.
Download the product description for Spicura Shield as a PDF here.
With PDRN, Sponge Spicules, and SPICURA, we demonstrate how innovative active ingredients from aesthetic medicine can be successfully integrated into modern cosmetic concepts.
Activate. Infuse. Shield.
We would be pleased to advise you on our raw materials, formulations, and application possibilities, or provide samples for your product development projects.
Kind regards,
Your GFN Team
P.S. Visit us at SEPAWA 2026 and discover our latest leave-on formulation featuring Sponge Spicules and PDRN from Laminaria digitata.
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